Snow is forecast to hit parts of the UK on Wednesday night along with heavy rain and strong winds.
Heavy and persistent snow is forecast in Scotland on Thursday morning, with 2cm to 5cm likely for many parts and up to 20cm on the highest ground, the Met Office said.
A yellow severe weather warning has been issued for northern Scotland, valid from midnight until 1pm on Thursday. It warns that some roads and railways are likely to be affected, with possible longer journey times for road, bus and train services.
Forecasters warn that spray and flooding on roads will make journey times longer while bus and train services are also likely to be affected.
Strong winds are also forecast, with a yellow weather warning in place for most of England until 7am on Thursday.
Met Office spokeswoman Nicola Maxey said: “Snow is forecast for northern Scotland and this could potentially affect travel in the area. Outside that area snow is not going to be an issue, it’s more likely to be heavy rain.
“The rain warning is in place until 9am tomorrow morning so will run over into the morning rush hour, so there could be spray on the roads, and at this time of year with leaves blown down we could see drains getting blocked up which could lead to surface water and flooding.”
In the Highlands, rail passengers are facing disruption after three landslips following heavy rain forced the cancellation of some services. Train services from Inverness to Kyle of Lochalsh and Wick have been affected, with the line blocked between the Highland capital and Beauly.
The Scottish Environment Protection Agency (Sepa) has issued flood alerts for Dumfries and Galloway and the Borders.
There are seven flood warnings in force outside Scotland, mostly in north-west England, and 19 flood alerts. A yellow warning for rain was also in place for parts of Northern Ireland on Wednesday.